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I use my refractometer to measure wort during mash. That way I can track changes and estimate when I'm maximizing conversion. To get a gravity reading for making calculations, I'll get a hydrometer reading. And, as I mentioned, I only use the gravity reading and accurate volume measurement after boil to calculate actual efficiency and OG. If you don't know anything other than SG before and after fermentation, it'll tell you about the attenuation and the alcohol content. Accurate volume readings are important for setting equipment profiles, tracking efficiencies and building recipes accurately.