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I believe I heard Dave Logston (a Wyeast big shot) say that if you make a starter with simple sugars, the yeast can loose their ability to convert more complex sugars. This would lead to an incomplete fermentation, and the beer flavor would be effected greatly. I agree with the 100% DME starter with a gravity around 1.040. If you save extra wort from a mash, you can also freeze it for longer storage. Just boil it up when you go to use it.